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Immune cell exosomes mediate innate and acquired immunity and play a dichotomous role: activating or suppressing immune responses, which affects cancer growth.
Intracellular and extracellular stimuli regulate their production, secretion, and uptake.
Most cell types, including immune cells, can secrete and uptake exosomes.
By that, they can transfer RNA, functional proteins, lipids, and metabolites to recipient cells in vivo
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Hence, immune cell-secreted exosomes may have applications in cancer diagnosis and immunotherapy and could be developed for vaccination and chemotherapy drug transporta…