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The biomarker framework has been developed for clinical diagnosis. It includes several key components such as the beta-amyloid 42 level, total tau, and phosphorylated tau (p-Tau) levels in cerebrospinal fluid (CSF). Additionally, it encompasses positron emission tomography (PET) amyloid imaging, Fluorodeoxyglucose uptake on PET, and structural magnetic resonance imaging (MRI).
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