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Cyclin-dependent kinase 4 (CDK4) inhibitors + Cyclin-dependent kinase 6 (CDK6) inhibitors (cdk4/6 inhibitors) + Endocrine therapy (ET) / Hormone therapy have demonstrated significantly improved progression-free survival (PFS) in patients with advanced Breast cancer / Mammacarcinoma (HR+ Her2-)
Cyclin-dependent kinase 4/6 inhibitors (CDKIs) are oral targeted agents approved for use in combination with endocrine therapy as first-line or second-line treatment of patients with Breast cancer / Mammacarcinoma (HR+ Her2-)
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