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25. März, 2018, 12:35
NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition; also shows activity against c-Raf, c-Src and c-Abl with IC50 of 0.395 μM, 1.266 μM and 1.667 μM, respectively. |
| Target: c-Src; EphB4; Tie-2; EphB4; c-Src; c-Raf; c-Abl; |