Medical Research Finder

Start
Features
Free trial / FAQ

Researchers
Physicians
Pharmacists
Ecotrophologists
Product Managers
in Health Industries

Loading…

© 2026 meRfi®

Medical Research Finder

Legal Notice
Privacy
Terms of Use

meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

AuthorsReferences (Sources)

meRfi® AI Chat

Chemotherapy (CT) (to improve) & Drugs/Treatments

Welcome to meRfi Microbiome!

Please register to continue your trial period!

meRfi Microbiome provides you with up-to-date, evidence-based insights on the gut microbiota and related health topics.

Access our ever-expanding digital library and get personalized answers through our interactive AI chat platform.

Start your free trial and transform your understanding of the gut microbiota today!

Register for a free trial

Navigation

Contents

Increasing of the efficacy

Fecal microbiota transplantation, short-term dietary manipulation of tryptophan and oral 3-IAA administration increase the efficacy of chemotherapy in humanized gnotobiotic mouse models of Pancreatic ductal adenocarcinoma (PDAC) / Pancreatic cancer
Tintelnot et al. 2023 Nature 615: 168–174

The efficacy of Indole-3-Acetic Acid (IAA, 3-IAA) and Chemotherapy (CT) is licensed by neutrophil-derived [myeloperoxidase](br…

References (Sources)

Effect of probiotics and gut microbiota on anti-cancer drugs: Mechanistic perspectives
Badgeley et al. 2021 Biochim Biophys Acta Rev Cancer 1875(1): 188494
Review
Gut microbiota and cancer: how gut microbiota modulates activity, efficacy and toxicity of antitumoral therapy
Gori et al. 2019
Intestinal microflora and digestive toxicity of irinotecan in mice
Brandi et al. 2006 Clin Cancer Res 12:1299-307
Involvement of beta-glucuronidase in intestinal microflora in the intestinal toxicity of the antitumor camptothecin derivative irinotecan hydrochloride (CPT-11) in rats
Takasuna et al. 1996 Cancer Res 56: 3752-7
Microbiota-derived 3-IAA influences chemotherapy efficacy in pancreatic cancer
Tintelnot et al. 2023 Nature 615: 168–174
Optimal antidiarrhea treatment for antitumor agent irinotecan hydrochloride (CPT-11)-induced delayed diarrhea
Takasuna et al. 2006 Cancer Chemother Pharmacol 1-10
The efficacy and safety of probiotics in people with cancer: a systematic review
Redman et al. 2014 Ann. Oncol. 25: 1919–1929
Review

AI Chat

7/2/2026

Chat with our artificial intelligence: