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Their intracellular domains are associated with zonula occludens (ZO) proteins that connect the junctional complexes with myosin 1C, an essential component of the actin cytoskeleton (5, 6).
Kinashi & Hase 2021 Front. Immunol. 12:673708
Kaminsky et al. 2021 Front. Immunol. 12: 767456 (1, 6, 21–23).
Myosin light chain kinase (MLCK) acts with Actomyosin Ring to regulate the contractility of actin fibers, thereby influencing tight junction structure and permeability (7, 8).
Kinashi & Hase 2021 Front. Immunol. 12:673708
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