Inhibitor of DNA-Binding Protein 2 (ID2)

Inhibitor of DNA-Binding Protein 2 (ID2) is crucial in the tumor infiltration and function of CD8 + T cells and that the antitumor efficacy of butyrate relies on Inhibitor of DNA-Binding Protein 2 (ID2) expression in CD8 + T cells
He et al. 2021c Cell Metabolism 33: 988-1000

Lack of Inhibitor of DNA-Binding Protein 2 (ID2) in CD8 +T cells also resulted in significant reduction of IL-12 receptor expression, which is critical for antitumor immunity (Tugues et al. 2015 Cell Death Differ 22: 237-246)
He…