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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

AuthorsReferences (Sources)

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Adiposity / Obesity & Pathomechanism

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Contents

Adiposity / Obesity has a multifactorial pathogenesis. Factors involved include:

Unhealthy lifestyle

Neuronal mechanisms

Hormonal mechanisms

Genetic factors

Epigenetic factors

Cerdó et al. 2019
Schütz et al. 2021
Młynarska et al. 2025 Curr Issues Mol Biol 47: 787

Environmental factors such as increased energy-rich, nutrient-poor food intake and a Sedentary lifestyle influence bacterial metabolism, including bacteria in the gastrointestinal tract, that is, the intestinal microbiota, which houses over 10H14 bacterial cel…

References (Sources)

ER stress in adiposity/obesity pathogenesis and management
Ajoolabady et al. 2022 Trends in Pharmacological Sciences 43: 97
Gender-specific differences in the association of adiponectin gene polymorphisms with body mass index
Tabatabaei-Malazy et al. 2010 Rev Diab Stud : RDS 7(3): 241-246
Methylenetetrahydrofolate reductase gene polymorphism in diabetes and adiposity/obesity
Tavakkoly Bazzaz et al. 2010 Mol Biol Rep 37(1): 105-109
Obesity as a multifactorial chronic disease: molecular mechanisms, systemic impact, and emerging digital interventions
Młynarska et al. 2025 Curr Issues Mol Biol 47: 787
Review
Prevalence of and risk factors for hepatic steatosis in Northern Italy
Bellentani et al. 2000 Ann Intern Med 132: 112-117
The Role of Probiotics and Prebiotics in the Prevention and Treatment of Obesity
Cerdó et al. 2019
Review
The role of the gut microbiota in energy metabolism and metabolic disease
Patrice & Nathalie 2009 Curr Pharm Des 15: 1546-1558.

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