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Pseudomonas exotoxin A (PE) has ADP-ribosylation activity and significantly impacts the protein synthesis of host cells
In recent years, the medical benefits of this molecule have been recognized. Several PE-based immunotoxins have been developed and tested in both preclinical and clinical trials for their efficacy against various cancers
see also:
Pseudomonas exotoxin & Antibody-Drug-Conjugates (ADCs)
Pseudomonas aeruginosa
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