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Although iDCs/LCs are efficient at taking up antigens, they are not as effective in presenting these antigens for T-cell activation until they mature
In their immature state, iDCs/LCs are highly endocytic, constantly sampling antigens from their environment
These cells express MHC class I molecules on their surface, which are essential for presenting antigenic peptides to CD8+ T cells
Langerhans cells express T-cell surface glycoprotein CD1a (CD1a), T-cell surface glycoprotein CD1b (CD1b), [T-cell surface …