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Oat-beta-glucan enhances anti-PD-1 (programmed cell death protein 1) efficacy in murine models by selectively expanding Faecalibacterium prausnitzii. Combining anti–PD-1 therapy with either oat β-glucan or F. prausnitzii enhances intratumoral dendritic-cell and CD8⁺ T-cell infiltration and cytotoxic activity compared with anti–PD-1 monotherapy. Metabolomic analyses identify F. prausnitzii–derived butyrate and [indole-3-propionic a…