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CD209 (Dendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin (DC-SIGN)) is a C-type lectin receptor predominantly expressed on immature dendritic cells and macrophages with potent endocytic capacity. This receptor plays a crucial role in the immune system by facilitating the recognition and uptake of various pathogens, including fungi like Candida albicans and viruses such as HIV-1. DC-SIGN functions as an antigen-uptake receptor, binding to specifi…