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Effector T-cells migrate from the mesenteric lymph nodes into the systemic circulation, where they can exert either pro-tumor or anti-tumor effects both in the tumor microenvironment (TME) and systemically.
The T cell connects with the tumor cell. It uses the T cell receptor (TCR) and the [CD279 (Programmed cell death protein 1 (PD-1)](brain://2N14L47SH0m1x…