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Eribulin is a novel microtubule inhibitor with mitotic and nonmitotic mechanisms of action.
Eribulin is a structurally simplified, synthetic macrocyclic ketone analog of halichondrin B, which is a natural, polyether macrolide derived from marine sponges. Eribulin exerts its cytotoxicity by its unique microtubule dynamics inhibitory action.
Seetharam et al. 2018…