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Activated Farnesoid X Receptor (FXR / NR1H4) also represses the expression of the pro-inflammatory transcription factors AP1 and NFKB and subsequent secretion of pro-inflammatory cytokines such as IL-1 beta and IL-6 and TNF / TNF-alfa , thereby promoting antimicrobial actions as well as the expression of CCL2 (also known as MCP1), one…