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Heart Failure / Congestive Heart Failure (CHF)
Osimertinib & Thromboembolism / Thrombosis
The data do not suggest a causal relationship between osimertinib and cardiac failure. However, because of LVEF decreases that were observed in patients with cardiac risk factors before osimertinib treatment, cardiac monitoring, including an assessment of LVEF at baseline and during osimertinib treatment, is advised.
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