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Tuft cells are a type of epithelial cell and are found in epithelial barriers throughout the body: the gastrointestinal tract, gallbladder, Nasal cavity, trachea, and thymus (6, 7, 8, 9). Most researchers now agree that tuft cells represent a particular epithelial cell type (15).
Intestinal tuft cells are a morphologically unique cell type, best characterized by striking microvilli that form an apical tuft. These cells represent approximately 0.5% of gut epithelial cells depending on location and are known to express chemosensory receptors .…