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Bacteria produce various substances that significantly impact the body's overall health, including how it processes food, fights off diseases, and maintains mental well-being (46, 47, 48). They, especially gut bacteria , produce unique enzymes that create diverse small molecules as intermediate or end products facilitating chemical communication between host and microbes (2, 3, 4, 5, 6, 7). The bacteria in the Gut microbiota have numerous genes involved in the biosynthesis of secondary metabolites (15).…