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Peptide YY (PYY) is a hormone produced by gut endocrine cells that plays a role in maintaining the balance of fungi in the digestive system of mammals, including controlling the growth of Candida albicans. Research has shown that Peptide YY, specifically the Paneth cell-derived form (PC-PYY), displays selective antifungal activity against virulent Candida albicans hyphae, contributing to the maintenance of gut fungal commensalism
This discovery deepens our understanding of the mycobiome and sugge…