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In the context of Carboplatin/Cisplatin + Pemetrexed + Tumor Treating Fields (TTFields) & Pleural Mesothelioma, Carboplatin/Cisplatin + Pemetrexed + Tumor Treating Fields (TTFields) is FDA‑ and EMA‑approved for unresectable pleural mesothelioma; the platinum backbone can be either carboplatin or cisplatin, and TTFields is delivered concomitantly as thoracic‑field therapy (1, 2).
The clinical phase II treatment trial, identified as NCT02397928 (STELLAR), demonstrated