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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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microRNA-122 (miR-122)

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microRNA‑122 (miR‑122) is found mainly in the liver. It makes up a large part of liver miRNA and plays a crucial role in liver health and function. miR‑122 is involved in liver diseases like cancer and viral hepatitis. It also affects immune system signals. miR‑122 is an important marker and treatment target in liver and cancer studies (1, 2, 3)

References:

(1) Xu et al. 2019 Elife 8: e41159
(2) Colaianni et al. 2024 Genes (Basel) 15(10): 1313
(3) Lashkarian et al. 2023 Cancer Cell Int 23(1): 29

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References (Sources)

MicroRNA-122 in human cancers: from mechanistic to clinical perspectives
Lashkarian et al. 2023 Cancer Cell Int 23(1): 29
Review
MicroRNA-122 supports robust innate immunity in hepatocytes by targeting the RTKs/STAT3 signaling pathway
Xu et al. 2019 Elife 8: e41159
Role of Circulating microRNAs in Liver Disease and HCC: Focus on miR-122
Colaianni et al. 2024 Genes (Basel) 15(10): 1313
Review

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