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A systematic review and meta-analysis, which included 40 animal studies and covered research up to May 2025, examined the effects of postbiotic supplementation on weight management, dietary intake, and metabolic indices in animal models of obesity. The findings showed that consuming postbiotics may have potential anti-obesity effects and improve metabolism by modulating the gut microbiota. This includes decreasing inflammation related to obesity, reducing the formation of fat cells, and enhancing lipid metabolism. However, to confirm these initial results, future clinical trials that are well-designed are necessary to assess their safety, effectiveness, and health benefits in humans (1)
Postbiotics, particularly [short-chain fatty…