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The transformation of bile acids by gut microbiota offers protection against infections from alfavirus, influenza virus, and coronavirus, indicating that this antiviral mechanism operates across different virus families and affects both local and systemic tissues.
Enteric eukaryotic viruses are increasingly recognized as non-pathogenic, immunomodulatory participants in the healthy gut microbiota.
The contributions of the viral component of the microbiome - the virome - to the development of innate and adaptive immunity are l…