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CD4- CD8+ Regulatory T cells (Tregs) and CD4 - CD8 - Regulatory T Cells (Tregs) can arise spontaneously (natural Treg) or be induced in situ.
Both CD4- CD8+ Regulatory T cells (Tregs) and CD4 - CD8 - Regulatory T Cells (Tregs) have been shown to enhance the survival of organ allografts and xenografts.
Additionally, both can suppress alloimmune responses by contact-dependent mechanisms by either inducing Apoptosis or mediating direct cytolysis of effector T cells.
CD4- CD8+ Regulatory T cells (Tregs) and [CD4 - CD8 …