XXX - Fluoxetine + Bifidobacterium breve + Bifidobacterium longum + Fructooligosaccharides (FOS) + Lacticaseibacillus casei + Lacticaseibacillus rhamnosus + Lactobacillus acidophilus + Lactobacillus delbrueckii bulgaricus + Streptococcus thermophilus vs Fluoxetine & Major depressive disorder / Major Depression / Depressive episode (MDD)

Background:

Major depressive disorder / Major Depression / Depressive episode (MDD) is a serious disorder that burdens modern societies, with a lifetime prevalence of about 16%. Disturbed immune responses in the gut and immune-privileged sites, including the central nervous system, might occur following dysbiosis of the gut microbiota (1)

Study overview:

It is a double-blind, placebo-controlled, multi-center, and randomized trial studying [Fluoxetine + Bifidobacterium breve + Bifidobacterium longum + Fructooligosaccharides (FOS) + Lacticaseibacillus casei + Lacticaseibac…