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published the results of ADT plus 1000 mg oral abiraterone acetate and 5 mg oral prednisone once daily or ADT plus placebo to patients with newly diagnosed, high-risk, metastatic castration-naive prostate cancer from a multicentre, international, randomized, phase III LATITUDE trial with 1199 subjects.
The authors' conclusion was: The addition of abiraterone acetate plus prednisone to ADT in patients with newly diagnosed, high-risk metastatic castration-naive prostate cancer improved overall PROs by consistently showing a clinical benefit in the progression of pain, prostate cancer symptoms, fatigue, functional decline, and overall HRQOL.
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