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Escherichia coli EcAZ-2 BSH is a developed, native Escherichia coli strain designed to permanently colonize the gut and express bile salt hydrolase
This strain is based on a native E. coli isolate (EcAZ-1) from mouse stool, which was first modified to produce green fluorescent protein (GFP) and kanamycin resistance, resulting in the traceable EcAZ-2 platform strain.
The EcAZ-2 strain was then further modified with the gene for bile salt hydrolase (BSH), resulting in EcAZ-2 BSH (sometimes writ…