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The exact role of bile acids and Farnesoid X Receptor (FXR / NR1H4) in controlling intestinal muco-epithelial as well as vascular permeability is still unknown
The permeability of the intestinal barrier is regulated by the FXR, among other things. Primary bile acids are among the most important activating agonists (; Yoneno et al. 2013).
Activate of the intestinal [Farnesoi…