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Primary outcome measures:
Number of Participants With Clinical Cessation of Status Epilepticus
In the context of benzodiazepine-refractory convulsive status epilepticus, the anticonvulsant drugs levetiracetam, fosphenytoin, and valproate each led to seizure cessation and improved alertness by 60 minutes in approximately half the patients, and the three drugs were associated with similar incidences of adverse events
Kapur et al. 2019 N Engl J Med 381: 2103-2113…