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Compounds such as L-histidinol and L-histidine hydroxamate are competitive inhibitors of histidine decarboxylase. These analogs bind to the active site of the enzyme, preventing the normal substrate (histidine) from being converted to histamine. This has been demonstrated in Micrococcus species, where these analogs effectively reduced Histidine decarboxylase activity
Bioactive Compounds from Seaweed and Plants: [Flavonoids](b…