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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Lactobacillus rhamnosus (genetically modified) pLR-GAA

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Lactobacillus rhamnosus (genetically modified) pLR-GAA means a genetically engineered strain of Lactobacillus rhamnosus GG ATCC 53103 that was transformed with a recombinant vector so it displays a GFP-Amuc_1100-anchor fusion protein on its cell surface. It showed anti-obesity, glucose-lowering, gut barrier–protective, anti-inflammatory, and tissue-protective effects in high-fat-diet-fed mice
Zhang et al. 2024 Bioengineering 11: 574

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The recombinant Lactobacillus strains with the surface-displayed expression of Amuc_1100 ameliorate obesity in high-fat diet-fed adult mice
Zhang et al. 2024 Bioengineering 11: 574

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7/1/2026

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Lactobacillus rhamnosus (genetically modified) pLR-GAA

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