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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

AuthorsReferences (Sources)

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Inflammatory Bowel Disease (IBD) & Leaky Gut Syndrome / Leaky Gut

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Contents

Disruption of the gut barrier is an essential mechanism of Inflammatory Bowel Disease (IBD) contributing to the development of mucosal inflammation.
Cao et al. 2020 Inflamm Bowel Dis. 26: 1340–1352

Numerous clinical studies have consistently shown that patients with ulcerative colitis and Crohn's disease have a significant increase in small bowel permeability

Halme et al. 2000 Scand J Clin Lab Invest 60(8): 695-701
Miele et al. 2007 Aliment Pharmacol Ther 25(8): 933-9
Benjamin et al. 2008 World J Gastroenterol (2008) 14(9): 1399-405
Dasty…

References (Sources)

Abnormal Intestinal Permeability in Crohn’s Disease Pathogenesis
Teshima et al. 2012 Ann N Y Acad Sci 1258: 159-65
Comparison of Iohexol and Lactulose-Mannitol Tests as Markers of Disease Activity in Patients With Inﬂammatory Bowel Disease
Halme et al. 2000 Scand J Clin Lab Invest 60(8): 695-701
Impaired Intestinal Permeability Contributes to Ongoing Bowel Symptoms in Patients With Inﬂammatory Bowel Disease and Mucosal Healing
Chang et al. 2017 Gastroenterology 153(3): 723-31
Increased Intestinal Permeability is Associated With Later Development of Crohn’s Disease
Turpin et al. 2020 Gastroenterology 159(6): 2092-100
Increased Small Intestinal Permeability in Ulcerative Colitis: Rather Genetic Than Environmental and a Risk Factor for Extensive Disease?
Büning et al. 2012 Inﬂamm Bowel Dis 18(10): 1932-9
Inflammatory bowel disease is associated with increased gut-to-blood penetration of short-chain fatty acids: A new, non-invasive marker of a functional intestinal lesion
Jaworska et al. 2019 Experimental Physiology 104: 1226-1236
Intestinal Permeability in Inﬂammatory Bowel Disease: Pathogenesis, Clinical Evaluation, and Therapy of Leaky Gut
Michielan & D’Inca 2015 Mediators Inﬂammation 2015: 628157

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