Secretory IgA in the coordination of establishment and maintenance of the microbiota

Starting at birth, the gut microbiota changes dramatically from a highly individual collection of microorganisms, dominated by comparably few species, to a mature, competitive, and diverse microbial community. Microbial colonization triggers and accompanies the maturation of the mucosal immune system and ultimately results in a mutually beneficial host-microbe interrelation in the healthy host.
Pabst et al. 2016 Trends Immunol. 37, 287-296…