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The European Medicines Agency's Committee for Medicinal Products for Human Use (EMA CHMP) has given a positive opinion indicating that Calquence TM can be used in combination with venetoclax, with or without obinutuzumab, for adults who have not previously been treated for chronic lymphocytic leukemia (CLL). Following this, in June 2025, the European Commission approved the use of a fixed-duration treatment involving acalabrutinib plus venetoclax, with or without obinutuzumab, for frontline CLL (1)
The triple combination Acalabrutinib + [Obinutuzumab](brain://MPWAb5o5_FaI-DR7cQUXUQ/Obinutuzuma…