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Bifidobacterium longum JDM301 has been shown to be effective in combating toxigenic Clostridioides (Clostridium) difficile through several mechanisms.
In vitro studies show a significant reduction of Clostridioides (Clostridium) difficile counts and toxin levels, specifically Clostridioides (Clostridium) difficile toxin A (TcdA, CdtA) and TcdB. This reduction is achieved by acidifying the environment, which leads to the degradation of the toxins.
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