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Ursodiol helps regulate cholesterol by reducing the absorptionrate of cholesterol molecules by breaking up micelles containing cholesterol.
Ursodeoxycholic Acid (UDCA) stimulates intestinal epithelial cell migration in-vitro and in-vivo via activation of the EGF receptor (EGFR)/COX-2 pathway, which is associated with protection against epithelial barrier destruction. This migration was blocked by inhibition of cyclooxygenase 2 (COX-2), epidermal growth factor receptor (EGFR), or ERK.
Golden et al. 2018 Am. J. Physiol. Gastrointest. Liver Physiol. 315: G259-G271
Ursodeoxyc…